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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCCC2
All Species:
46.36
Human Site:
S342
Identified Species:
85
UniProt:
Q9HCC0
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCC0
NP_071415.1
563
61333
S342
I
A
R
I
V
D
G
S
R
F
T
E
F
K
A
Chimpanzee
Pan troglodytes
XP_517717
563
61220
S342
I
A
R
I
V
D
G
S
R
F
T
E
F
K
A
Rhesus Macaque
Macaca mulatta
XP_001096794
563
61647
S342
I
A
R
I
V
D
G
S
R
F
T
E
F
K
A
Dog
Lupus familis
XP_535268
563
61534
S342
I
A
R
I
V
D
G
S
R
F
S
E
F
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3ULD5
563
61361
S342
I
A
R
I
V
D
G
S
R
F
N
E
F
K
A
Rat
Rattus norvegicus
Q5XIT9
563
61499
S342
I
A
R
I
V
D
G
S
R
F
N
E
F
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001091355
562
61332
S341
I
A
R
V
V
D
G
S
K
F
D
E
F
K
A
Zebra Danio
Brachydanio rerio
NP_998092
566
61725
S345
I
A
R
I
V
D
G
S
K
F
D
E
F
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V9A7
578
62630
S357
I
A
R
I
V
D
G
S
R
F
T
E
F
K
K
Honey Bee
Apis mellifera
XP_394033
559
61367
S338
I
A
R
I
V
D
G
S
K
F
R
E
F
K
A
Nematode Worm
Caenorhab. elegans
P34385
608
66505
S387
I
A
R
I
V
D
G
S
R
F
H
E
F
K
E
Sea Urchin
Strong. purpuratus
XP_001201046
552
59601
S331
I
A
R
V
V
D
E
S
V
F
D
E
F
K
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LDD8
587
63994
A360
F
D
V
R
S
I
I
A
R
I
V
D
G
S
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
93
87.9
N.A.
88.8
88.2
N.A.
N.A.
N.A.
81.5
81
N.A.
67.4
69
59.2
65.5
Protein Similarity:
100
99.1
95.3
93.7
N.A.
94.3
94.3
N.A.
N.A.
N.A.
90.4
89.2
N.A.
78.7
82.5
74.5
79.5
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
80
86.6
N.A.
93.3
86.6
86.6
66.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
93.3
93.3
N.A.
93.3
93.3
86.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
58
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
73
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
93
0
0
0
0
0
8
0
0
0
0
0
0
70
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
93
0
0
0
0
24
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
0
0
0
93
0
0
16
% E
% Phe:
8
0
0
0
0
0
0
0
0
93
0
0
93
0
0
% F
% Gly:
0
0
0
0
0
0
85
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
93
0
0
77
0
8
8
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
24
0
0
0
0
93
8
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
93
8
0
0
0
0
70
0
8
0
0
0
0
% R
% Ser:
0
0
0
0
8
0
0
93
0
0
8
0
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
31
0
0
0
0
% T
% Val:
0
0
8
16
93
0
0
0
8
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _